Product Benefits
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Rapid, effective allergy relief: Controls symptoms like sneezing, runny nose, itchy/watery eyes, nasal itching, and hives associated with allergic rhinitis and chronic urticaria
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Minimal sedation: Being a second-generation antihistamine, Afexa does not cross the blood–brain barrier—most users report little or no drowsiness.
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Once-daily regimen: Simplified dosing improves adherence. Offers flexibility of 120 mg once daily or 60 mg twice daily.
Dosage & Administration
| Indication | Recommended Dose |
|---|---|
| Seasonal & perennial allergic rhinitis, chronic urticaria | 120 mg once daily or 60 mg twice daily for adults ≥12 yrs |
| Chronic idiopathic urticaria | Up to 180 mg once daily |
| Renal impairment (eGFR <80 mL/min) | Reduce to 60 mg once daily |
| Take on an empty stomach, and avoid fruit juices (e.g., grapefruit, orange, apple) or antacids within 1–2 hours to prevent absorption interference. |
Safety, Side Effects & Precautions
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Common side effects: Headache (5–10%), nausea, cough, back pain, dizziness, upper respiratory infections, drowsiness (1–3%).
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Contraindications: Hypersensitivity to fexofenadine or formulation components.
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Precautions: Adjust dose for renal patients, exercise caution in elderly or those with cardiovascular conditions due to possible tachycardia or palpitations. Avoid combination with potent CYP3A4 inhibitors/inducers (e.g., erythromycin, ketoconazole, rifampin).
Pricing & Packaging
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Manufacturer: UniMed UniHealth Pharmaceuticals Ltd., Bangladesh
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Alternative brands: Comparable 120 mg fexofenadine tablets in Bangladesh include Adifex, Fexofen (Somatec), Dinafex (Eskayef), Fenox, Alagra, Telfast (imported) with prices ranging from
Summary Table
| Feature | Details |
|---|---|
| Generic Substrate | Fexofenadine Hydrochloride 120 mg |
| Brand / Maker | Afexa (UniMed UniHealth, Bangladesh) |
| Main Indications | Allergic rhinitis (seasonal/perennial), chronic urticaria |
| Typical Dose | 120 mg once daily or 60 mg BID |
| Max Dose (Adults) | Up to 180 mg/day for urticaria |
| Common ADRs | Headache, nausea, fatigue, slight drowsiness |
| Prescription Status | Prescription-only |
Afexa and equivalent fexofenadine tablets are commonly available OTC in Bangladesh. They are favored for allergy relief without sedation. However, expert consultation is advised, especially if using other medications or managing chronic conditions.
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