✅ Product Benefits

1. Enhanced blood pressure control by dual mechanism
   Bisoprolol (β₁-selective blocker) reduces heart rate and cardiac output, while low-dose Hydrochlorothiazide (6.25 mg) promotes diuresis—together providing additive antihypertensive effects with reduced risk of hypokalemia compared to higher-dose thiazides. 

2. Convenient once-daily dosing and flexible titration
   Begin at 2.5 mg/6.25 mg once daily, increasing every 2 weeks if needed up to 5/6.25 or 10/6.25 or max 20/12.5 mg/day for adequate control. 

3. Reduced electrolyte disturbance risk
   The combination helps minimize potassium loss associated with thiazides and lowers fluid retention risk, improving tolerability. 

4. Well-established safety and tolerability
   Common side effects are generally mild and transient—fatigue, dizziness, headache, bradycardia, orthostatic hypotension, peripheral coldness; contraindications include cardiogenic shock, severe bradycardia, heart block, and hypersensitivity to sulfonamides. 

5. Useful in heart failure and angina settings
   Can be used adjunctively in chronic stable heart failure or chronic stable angina when combined with ACE inhibitors and diuretics. 

6. Available and affordable in Bangladesh
   Priced at approximately ৳10 per tablet (~৳100 per 10‑tablet strip), readily accessible nationwide. 

7. Convenient administration
   May be taken with or without food, enhancing patient compliance.