• Optimizes microvascular circulation: Enhances endothelial integrity, reduces capillary permeability, decreases serum viscosity, and inhibits platelet aggregation to improve tissue perfusion. 

• Reduces symptoms of venous insufficiency: Helps relieve leg pain, cramps, numbness, swelling, stasis-related skin changes (dermotosis), and discomfort from hemorrhoidal syndrome. 

• Supports diabetic microangiopathy management: Used adjunctively in diabetic retinopathy and peripheral microvascular complications. Simple dosing schedule: Typically taken once or twice daily with main meals. Dosing is individualized and may span from several weeks to months, depending on disease severity. 

• Cost-effective & locally available: Unit price around ৳ 20; a strip of 10 capsules is typically priced at ৳ 200 in Bangladesh. Available via pharmacies and online retailers. 

ℹ️ Usage & Safety Information

• Adult dosage: 500 mg capsule taken once or twice daily during main meals. Duration usually ranges from a few weeks to several months. Dosing tailored per condition severity. 

• Contraindications & Cautions:

  • Not suitable for individuals with known hypersensitivity to calcium dobesilate.

  • Severe renal impairment (especially dialysis patients) may require dose reduction.

    Side effects:

• • Occasionally causes nausea, diarrhea, skin rash, fever, joint pain.

  • Very rarely, agranulocytosis—patients should seek medical attention if they develop flu-like symptoms. Reversible upon cessation. 

• Pregnancy & breast‑feeding:

  • Safety data lacking. Should only be used if the expected benefit outweighs potential risks.

  • Calcium dobesilate may pass minimally into breast milk (≈0.4 µg/mL). Breast-feeding discontinuation may be advisable. 

• Overdose: Clinical signs are unknown. Seek medical attention immediately in case of accidental ingestion. 

• Storage: Keep below 30 °C, in a dry, light-protected place. Store out of children's reach. 

✅ Quick Summary Table