• Neuroprotective and cognitive support: Citicoline enhances phospholipid synthesis in neuronal membranes, increases acetylcholine and dopamine levels, and improves cerebral blood flow—supporting recovery from ischemic stroke, head injury, and neurodegenerative conditions. 

• Facilitates stroke and traumatic brain recovery: Initiating treatment within 24 hours of an ischemic stroke may improve the chances of full functional recovery within 3 months; useful also for attention deficit and cerebral insufficiency due to head trauma. 

• Supports neurodegenerative and vascular cognitive decline: Used adjunctively in Alzheimer's disease and Parkinsonian dementia, helping slow cognitive deterioration and enhance memory, focus, and motor function. 

• Flexible, clinician‑tailored dosing: Oral dosages typically range from 500–2000 mg/day in divided doses, depending on severity. Intravenous or intramuscular administration may be used in acute hospital settings. 

• Economical & widely available: Priced at approximately ৳ 50 per tablet (৳ 500 for a 10‑tablet strip), and accessible across pharmacies and online platforms in Bangladesh. 

ℹ️ Usage & Dosing Guidelines

• Stroke (ischemic) and traumatic brain injury: 500–2000 mg orally per day, started ideally within 24 hours of event. Higher daily doses used initially and stepped down post-recovery. Since Cogniz is 500 mg, it may be given 1–4 times daily depending on therapeutic need. 

• Chronic cerebrovascular insufficiency or cognitive disorders: Up to 1000 mg daily in divided doses, with meals or between meals. Elderly patients generally do not require dose adjustment. 

• Administration: Can be taken with or without food; consistent timing is recommended.

⚠️ Safety & Precautions

• Side effects: Generally well tolerated—may include insomnia, headache, gastrointestinal discomfort, drop/rise in blood pressure, blurred vision, arrhythmia, or chest tightness. 

• Precautions:

  • May cause drowsiness or dizziness—avoid operating machinery until response is known.

  • May lower blood pressure; hypotension may require management with steroids or sympathomimetic agents.

  • Slow IV administration (≈30 drops/min) is advised in intracranial hemorrhage to avoid sudden cerebral perfusion changes. Monitor vital signs. 

• Drug interactions: Enhances effect of levodopa/carbidopa and entacapone in Parkinson’s therapy; avoid co-administration with meclophenoxate derivatives. Alcohol consumption should be avoided. 

• Contraindications: Known hypersensitivity to citicoline or cholinergic compounds; caution if parasympathetic system hyperactivity is suspected. 

• Pregnancy & breastfeeding: Insufficient data; use only if benefits clearly outweigh potential risks. 

• Storage: Store below 30 °C in a dry environment, away from light. Keep out of children’s reach. 

🧾 Quick Overview Table

ℹ️ Additional Notes

• Early initiation (within 24 h) post-stroke is associated with better neurological recovery.

• While cognition-enhancing effects may be felt within hours (as early as 30 minutes), maximum clinical benefit often requires weeks of consistent therapy.