• Broad-spectrum antifungal activity: Effective against a wide range of fungal pathogens including Candida species, Cryptococcus neoformans, and dermatophytes causing tinea infections.

• Convenient dosing regimen: For many indications, a single 150 mg dose is sufficient, enhancing patient compliance.

• High bioavailability: Approximately 90% oral bioavailability, ensuring effective systemic concentrations.

• Minimal food interaction: Can be taken with or without food, offering flexibility in administration.

• Affordable pricing: Priced at approximately ৳ 20.06 per capsule, making it an economical choice for antifungal therapy in Bangladesh.

✅ Indications & Dosage

• Vaginal candidiasis: 150 mg as a single oral dose.

• Oropharyngeal candidiasis: 200 mg on the first day, followed by 100 mg daily for 14 days.

• Esophageal candidiasis: 200 mg on the first day, followed by 100 mg daily for 14–30 days.

• Tinea infections (e.g., corporis, cruris, pedis): 150 mg weekly for 4–6 weeks.

• Onychomycosis: 150 mg weekly for 6–12 months.

• Cryptococcal meningitis: 400 mg on the first day, followed by 200 mg daily.

• Systemic candidiasis: Doses up to 400 mg daily may be used.

• Prophylaxis in immunocompromised patients: 50–400 mg daily, depending on the risk.

✅ Side Effects

• Common: Nausea, headache, abdominal pain, diarrhea, dizziness.

• Serious: Hepatotoxicity, QT prolongation, skin rash, allergic reactions.

• Rare: Seizures, hallucinations, and paranoia in overdose situations.

✅ Drug Interactions

• Increased plasma levels: Cyclosporine, phenytoin, warfarin.

• Decreased plasma levels: Rifampin.

• QT prolongation risk: Caution with other QT-prolonging agents.

✅ Storage Instructions

• Store in a cool, dry place below 30°C.

• Keep out of reach of children.

• Protect from light and moisture.