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Detrusin LA 4mg Capsule

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15.00 Tk

✅ Product Benefits

  • Once-daily extended-release convenience: A 4 mg ER capsule provides stable blood levels and sustained relief throughout the day for bladder symptoms. turn0search0turn0search7

  • High bladder specificity with fewer systemic effects: Tolterodine preferentially targets bladder muscarinic receptors, minimizing dryness and sedation compared to non-selective anticholinergics. turn0search0turn0search11

  • Rapid onset of symptom relief: Improvement may occur within 4 weeks of consistent use. turn0search11turn0search0

  • Local availability at affordable cost: Widely available across Bangladesh, priced at approximately ৳ 15 per capsule (৳ 300 per 20-cap pack). turn0search0turn0search2


ℹ️ Dosage & Administration

Patient GroupRecommended Dose
Adults ≥18 years4 mg once daily, with or without food
If side effects presentReduce to 2 mg once daily
With CYP3A4 inhibitors / hepatic or renal impairmentLimit to 2 mg once daily
Pediatric useNot recommended

Swallow the capsule whole—do not chew or crush. Full therapeutic effect may take up to 4 weeks. turn0search0turn0search6


⚠️ Safety, Side Effects & Precautions

  • Contraindications:

    • Uncontrolled narrow-angle glaucoma

    • Urinary retention or gastrointestinal obstruction (e.g., megacolon)

    • Hypersensitivity to tolterodine or excipients turn0search0turn0search7

  • Common side effects:
    Dry mouth (~23 %), constipation, headache, dizziness, blurred vision, dry eyes. These anticholinergic effects are more common at therapeutic doses. turn0search0turn0search10

  • Cardiac and drug interaction warnings:

    • Use cautiously in patients with known QT prolongation or taking QT‑prolonging drugs (e.g. antiarrhythmics).

    • Potent CYP3A4 inhibitors (e.g. ketoconazole, erythromycin, clarithromycin, protease inhibitors) significantly increase plasma levels—dose reduction to 2 mg advised. turn0search0turn0search7turn0search10

  • Special populations:

    • Elderly: No significant safety difference, but start at lower dose if needed.

    • Renal/hepatic impairment: Use low dose (2 mg once daily); severe impairment contraindicated.

    • Pregnancy & breastfeeding: Animal studies show potential risk; avoid unless benefit outweighs risk. Excretion in breast milk unknown—milk production may be reduced. turn0search0turn0search6

  • Overdose: May result in severe anticholinergic symptoms (e.g., delirium, tachycardia)—ECG monitoring advised. turn0search10turn0search9


✔️ Quick Summary Table

FeatureDetails
Generic nameTolterodine Tartrate 4 mg (extended-release)
IndicationOveractive bladder symptoms (urgency, frequency, urge incontinence)
Dose (adults)4 mg once daily (ER capsule)
Side effectsDry mouth, constipation, dizziness, blurred vision
Major warningsQT prolongation risk, urinary retention, CYP3A4 inhibitors
Approx. Price (BD)৳ 15 per capsule; ৳ 300 per 20-capsule pack
ManufacturerUniMed UniHealth Pharmaceuticals Ltd., Bangladesh

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