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Product Benefits
| Core Benefit | Mechanism |
| Synergistic $\text{BP}$ Reduction | The combination of a $\text{CCB}$ and an $\text{ARB}$ provides a greater overall blood pressure lowering effect than either component used alone, effectively addressing multiple underlying causes of hypertension. |
| Cardioprotection and Renal Protection | Olmesartan ($\text{ARB}$) offers specific protective effects for the heart and kidneys, which is highly valuable for patients with chronic hypertension. |
| Convenient Once-Daily Dosing | The fixed combination simplifies the treatment regimen to a single daily tablet, significantly improving patient adherence for long-term blood pressure control. |
| May Mitigate Edema | The vasodilating effects of Olmesartan can sometimes help reduce the peripheral edema (ankle swelling) commonly associated with Amlodipine monotherapy. |
⚠️ Important Safety Note: Angiotensin II Receptor Blocker ($\text{ARB}$) Component
Prescription Required: This medication must be taken strictly as prescribed.
Fetal Toxicity (Black Box Warning): DO NOT use this medication if you are pregnant or planning to become pregnant. Olmesartan ($\text{ARB}$) can cause injury and death to the developing fetus, particularly during the second and third trimesters. If pregnancy is detected, discontinue this medication immediately.
Hypotension: May cause dizziness or light-headedness, especially when rising quickly from a seated or lying position.
Kidney/Electrolyte Monitoring: Patients should have their kidney function, potassium, and other electrolyte levels closely monitored by a physician during treatment.
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