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Product Benefits
| Core Benefit | Mechanism |
| Superior Blood Pressure Control | Combining two distinct classes of powerful anti-hypertensives provides a synergistic effect, resulting in a greater blood pressure reduction than either component alone, especially effective for resistant hypertension. |
| Renal and Cardioprotection | Olmesartan ($\text{ARB}$) offers specific protection to the kidneys and heart by blocking the harmful effects of Angiotensin II, which is crucial for patients with hypertension. |
| Convenient Once-Daily Dosing | The fixed combination is taken once daily, significantly simplifying the treatment regimen and improving patient compliance for long-term chronic management. |
| Reduced Side Effects | The combination often allows for the use of lower doses of Amlodipine, which may reduce the incidence of peripheral edema (ankle swelling), a common side effect of $\text{CCBs}$ alone. |
⚠️ Important Safety Note: Angiotensin II Receptor Blocker ($\text{ARB}$) Component
Prescription Required: This medication must be taken strictly as prescribed.
Fetal Toxicity (Black Box Warning): DO NOT use this medication if you are pregnant or planning to become pregnant. Olmesartan ($\text{ARB}$) can cause injury and death to the developing fetus, particularly during the second and third trimesters. If pregnancy is detected, discontinue this medication immediately.
Hypotension: May cause dizziness or light-headedness, especially upon standing, particularly during the initial days of therapy.
Kidney/Electrolyte Monitoring: Patients should have their kidney function, potassium, and other electrolyte levels closely monitored by a physician, especially when taking other medications that affect the kidneys (like $\text{NSAIDs}$).
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