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Product Benefits
| Core Benefit | Mechanism |
| Superior $\text{BP}$ Control | The combination leverages two different physiological pathways to reduce vascular resistance and blood volume, resulting in a more potent and reliable blood pressure lowering effect than single-drug therapy. |
| Tissue Protection | Enalapril ($\text{ACE}$ Inhibitor) offers well-documented cardio- and renal-protective benefits, which are crucial for patients with long-standing hypertension. |
| Reduced Edema Risk | The combination often uses lower, optimized doses of the $\text{CCB}$ (Lercanidipine is known for low edema risk), and the $\text{ACE}$ inhibitor may counteract $\text{CCB}$-induced peripheral edema, a common side effect. |
| Convenient Once-Daily Dosing | The fixed combination is taken once daily, significantly simplifying the treatment regimen and improving patient adherence for long-term chronic management. |
⚠️ Important Safety Note: $\text{ACE}$ Inhibitor Component
Prescription Required: This medication must be taken strictly as prescribed.
Fetal Toxicity (Black Box Warning): DO NOT use this medication if you are pregnant or planning to become pregnant. $\text{ACE}$ inhibitors can cause injury and death to the developing fetus, particularly during the second and third trimesters.
1 If pregnancy is detected, discontinue this medication immediately.Angioedema Risk: Enalapril can cause Angioedema (swelling of the face, lips, tongue, or throat).
2 Seek immediate emergency medical care if you experience any swelling or difficulty breathing.Cough: A persistent, dry cough is a common side effect of
3 $\text{ACE}$ inhibitors and should be reported to your doctor.
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