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Product Benefits
| Core Benefit | Mechanism/Effect |
| Significant Triglyceride Reduction | Highly effective in lowering total triglycerides and $\text{VLDL}$, primarily by increasing the breakdown and elimination of triglyceride-rich particles from the plasma. |
| Improves $\text{LDL}$ Quality | Produces an alteration in the size and composition of $\text{LDL}$ particles, converting small, dense (atherogenic) particles into larger, less harmful particles. |
| Boosts $\text{HDL}$ Cholesterol | Treatment leads to beneficial increases in $\text{HDL}$ ("good") cholesterol levels. |
| Reduces $\text{Serum}$ $\text{Uric}$ $\text{Acid}$ | Fenofibrate increases the urinary excretion of uric acid, which is beneficial for patients with high cholesterol who also have hyperuricemia. |
⚠️ Critical Safety Warning: Fenofibrate Use
Contraindications: This medication is contraindicated in patients with severe renal or hepatic impairment, existing gall bladder disease, and those hypersensitive to Fenofibrate.
23 Monitoring: Liver function tests ($\text{LFT}$s) are recommended every 3 months for the first year of treatment.
24 Myotoxicity: Caution should be taken when using Fenatrol with
25 $\text{HMG-CoA}$ reductase inhibitors (Statins) due to a potential increase in the risk of rhabdomyolysis (muscle damage).26
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