✅ Product Benefits
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Potent systemic & mucosal antifungal
Effective for oropharyngeal/esophageal/vaginal candidiasis; dermatophyte infections like tinea; cryptococcal meningitis; systemic candidiasis; prophylaxis in immunocompromised individuals. -
Simple once‑daily oral dosing
Adults typically take 200 mg on day 1 followed by 100 mg daily; doses may escalate to 400 mg/day depending on severity and patient response. -
Excellent absorption & long half-life
Fluconazole features >90% oral bioavailability and ~30‑hour half-life, allowing for effective, steady plasma levels with easy oral dosing. -
Low incidence of side effects
Most common: nausea, abdominal discomfort, diarrhea, headache, rash. Rare but serious risks include hepatotoxicity, QT prolongation, and severe cutaneous adverse reactions. -
Significant drug interaction profile
Inhibits CYP2C19, CYP3A4, and CYP2C9—can increase blood levels of warfarin, phenytoin, cyclosporine; rifampicin can reduce efficacy. Monitor therapy accordingly. -
Used with caution during pregnancy or breastfeeding
Avoid in pregnancy (Category C risk for fetal abnormalities); excreted in breast milk—contraindicated unless benefits outweigh risks. -
Adjust dosing in renal impairment
May require extended dosing intervals in low creatinine clearance (<41 mL/min), especially in multi-dose regimens. -
Cost‑effective & readily accessible
Priced approx ৳25 per capsule (strip of 6 costs ৳151), widely stocked in pharmacies and online outlets across Bangladesh.
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