💡 Uses & Benefits
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Neuropathic Pain: Effective against conditions like postherpetic neuralgia and diabetic neuropathy, reducing burning or shooting nerve pain (Day 1: 300 mg once, Day 2: twice, then Day 3: thrice; up to 1,800 mg daily)
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Adjunctive Epilepsy Treatment: For partial-onset seizures (with or without secondary generalization), in adults and children aged ≥3 years, in combination with other antiepileptics
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Also used off-label for fibromyalgia, restless legs syndrome, hot flashes, headache syndromes, and behavioral disturbances in conditions like PTSD and MS
📋 Dosage & Administration
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Adults: Start with 300 mg once daily on Day 1, 300 mg twice on Day 2, then 300 mg three times on Day 3; titrate upward as needed (range: 900–1,800 mg/day in three divided doses; in epilepsy up to 2,400 mg/day as tolerated)
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Children (3–12 years): 10–15 mg/kg/day in 3 divided doses, titrated up to 25–35 mg/kg/day as needed
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Renal Impairment: Dose adjustment required in renal dysfunction; reduce per creatinine clearance guidelines
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Administration: Can be taken with or without food; swallow whole with water
⚠️ Side Effects & Precautions
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Common: Drowsiness, dizziness, fatigue, somnolence, ataxia, peripheral edema, weight gain, dry mouth (>5–10%)
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Uncommon/Rare: Mood changes, depression, memory impairment, blurred vision, headache, leukopenia, rash; rare cases of hepatic failure or aplastic anemia reported
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Warnings: May increase suicidal thoughts in vulnerable patients (monitor mental health closely); avoid abrupt discontinuation—taper off gradually
🚫 Contraindications & Interactions
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Contraindicated in known hypersensitivity to gabapentin
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Drug Interactions:
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Antacids may reduce absorption by ~20%—separate dosing by ≥2 hours
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Cimetidine may reduce renal elimination slightly
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Minimal interaction with other antiepileptics or oral contraceptives observed
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👶 Pregnancy & Lactation
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Pregnancy Category C: Use only if potential benefits justify fetal risk
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Breastfeeding: Gabapentin is excreted in breast milk—use only if benefit outweighs risk, monitor infant for sedation or feeding issues
📦 Product Details & Pricing (Bangladesh)
| Attribute | Information |
|---|---|
| Generic Name | Gabapentin |
| Brand Name | Gabastar 300 mg Tablet |
| Manufacturer | Square Pharmaceuticals Ltd. |
| Price per Tablet | ৳ 16.11 (strip of 10 tablets ≈ ৳161.10) |
| Storage | Below 25 °C, protected from light and moisture; keep out of reach of children |
✅ Summary Table
| Feature | Overview |
|---|---|
| Active Ingredient | Gabapentin 300 mg |
| Indications | Neuropathic pain; adjunct for partial seizures |
| Starting Dose | 300 mg once → 300 mg TID by Day 3 |
| Maintenance Range | 900–1,800 mg/day |
| Benefits | Reduces nerve pain, tremors; seizure adjunct with minimal interactions |
| Common Side Effects | Drowsiness, dizziness, fatigue, ataxia, weight gain |
| Special Precaution | Monitor mental health, taper off gradually |
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