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General Actions (Not specific medical benefits for the user)
| Core Action | Mechanism |
| Reduces Bile Acid Toxicity | Obeticholic Acid activates the Farnesoid X Receptor (FXR), which is a key regulator of bile acid production. This action suppresses the synthesis of bile acids in the liver, reducing the overall circulating bile acid pool. |
| Treats PBC | By decreasing the toxic levels of bile acids within liver cells (hepatocytes), it helps to reduce liver inflammation and fibrosis associated with Primary Biliary Cholangitis. |
| Promotes Choleresis | FXR activation helps in increasing the transport of bile acids out of the hepatocytes and promoting bile flow (choleresis), thus reducing damage caused by bile acid accumulation. |
| Monotherapy/Combination Option | Provides a therapeutic option for PBC patients who either cannot tolerate UDCA (monotherapy) or require enhanced biochemical response beyond what UDCA alone provides (combination therapy). |
⚠️ Important Safety Note:
Livcare 5mg Tablet is a specialized prescription medication. It is contraindicated in patients with complete biliary obstruction.
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