✅ Product Benefits

• Rapid onset on-demand action: Taken 1–3 hours before intercourse, dapoxetine typically reaches peak plasma levels within 1–2 hours and begins working within that window to delay ejaculation. ([turn0search4]turn0search3])

• Convenient dosing regimen: Initially prescribed as a single 30 mg oral dose; if needed and tolerated, may be increased to 60 mg. Maximum once daily. ([turn0search2]turn0search5])

• Effective for most PE patients: Particularly suited for men experiencing recurrent ejaculation with minimal stimulation and resulting in personal or interpersonal distress. ([turn0search0]turn0search4])

• Low risk of sexual dysfunction: Unlike many conventional SSRIs used off-label for PE, dapoxetine has minimal impact on libido and erectile function. (<1% sexual dysfunction; <4% ED) ([turn0search1])

• Widely available and affordable: Sold in 4‑ or 8‑tablet packs, priced around ৳ 15–20 per tablet (strip of 4 for ৳ 80). Flagship dapoxetine brand in Bangladesh. ([turn0search0]turn0search7])

ℹ️ Precautions & Safety Notes

• Contraindications:

  • Known allergy to dapoxetine or SSRIs.

  • Significant cardiac conditions (e.g., heart failure NYHA II–IV, AV block, sick sinus syndrome untreated by pacemaker, valvular disease).

  • Use within 14 days of MAOIs, TCAs, SSRIs/SNRIs, or thioridazine. These medications should not be started within 7 days after dapoxetine discontinuation. ([turn0search0]turn0search2])

• Side effects:

  • Common (>5%): nausea, dizziness, headache, somnolence, tremor, blurred vision, tinnitus, sinus congestion, dry mouth, abdominal discomfort, diarrhea, fatigue, insomnia, hypertension. Discontinuation due to adverse effects increases with higher dose. ([turn0search1]turn0search4]turn0search2])

• Precautions:

  • Orthostatic hypotension and syncope may occur; perform orthostatic test prior to use. Avoid use in patients at risk. ([turn0search1]turn0search2])

  • Combining with alcohol or recreational drugs increases risk of dizziness, drowsiness, and syncope. ([turn0search1]turn0search2])

  • Use cautiously in individuals on anticoagulants or with bleeding disorders due to reports of SSRIs affecting platelet function. ([turn0search1]turn0search2])

• Special populations:

  • Not indicated in women or children.

  • No safety data in pregnancy or breastfeeding.

  • Use with caution in hepatic impairment; moderate-to-severe hepatic dysfunction is contraindicated. ([turn0search5]turn0search2])

  • No dose adjustment typically needed in mild to moderate renal impairment, but caution advised. ([turn0search2])

• Drug interactions:

  • Co-administration with CNS depressants (e.g., sedatives, opioids) may enhance sedation.

  • Tadalafil and sildenafil have minimal impact on dapoxetine pharmacokinetics, but caution is advised since combination may reduce orthostatic tolerance. ([turn0search1]turn0search3])

• Overdose:

  • Doses up to 240 mg have been tolerated in studies. Overdose symptoms include serotinergic effects, nausea, vomiting, tachycardia, tremor, agitation, dizziness. Supportive treatment advised. ([turn0search1]turn0search6])

• Storage: Store below 30 °C, protected from light and moisture; keep out of reach of children. ([turn0search0]turn0search10])

✔️ Summary Table