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Prazopress-ER 2.5mg Tablet

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12.00 Tk

Product Benefits

  • Extended-release convenience: Provides steady prazosin release once daily—improves adherence and reduces blood pressure fluctuations.

  • Treats multiple conditions: Indicator for hypertension, BPH-related urinary obstruction, Raynaud’s phenomenon, and congestive heart failure resistant to other therapies. 

  • Lowers vascular resistance safely: Selectively blocks alpha‑1 receptors to relax vessels, lower diastolic BP, and enhance blood flow—without reflex tachycardia. 


Dosage & Administration

IndicationDose Guidelines
HypertensionStart at 2.5 mg once daily at bedtime; titrate up cautiously based on response.
Benign Prostatic HyperplasiaBegin with 0.5–1.0 mg in evening, then increase to typical 2 mg twice daily if needed.
Raynaud’s Phenomenon0.5 mg twice daily, adjust per clinical response over 3–7 days.
Congestive Heart FailureStart at 0.5 mg two–four times daily, increasing gradually to 4–20 mg total daily.
  • May be taken with or without food; initial dose ideally 2–3 hours before sleep to minimize first-dose hypotension. 


Safety & Precautions

  • Common side effects: Dizziness, dizziness when standing, headache, drowsiness, weakness, palpitations, syncope, blurred vision, insomnia, fatigue. 

  • Drug interactions: Caution when co-administered with PDE‑5 inhibitors (e.g. sildenafil), beta-blockers, diuretics—risk of profound hypotension. Avoid alcohol.Contraindications & warnings:

    • Not recommended in patients with hypersensitivity to quinazolines.

    • Use cautiously in those with orthostatic hypotension, hepatic or renal impairment, or history of micturition syncope.

    • Pregnancy Category C; use only if benefits outweigh risks. Excreted in breast milk—avoid while breastfeeding unless advised. 

  • Overdose management: Treat hypotension with fluid resuscitation and vasopressors if needed; symptomatic care; activated charcoal if early ingestion. 


Quick Facts Table

FeatureDetails
Generic NamePrazosin Hydrochloride 2.5 mg ER Tablet
Brand / ProducerPrazopress‑ER (UniMed UniHealth Pharmaceuticals, Bangladesh)
IndicationsHypertension, BPH symptoms, Raynaud’s phenomenon, heart failure
Starting Dose2.5 mg once daily (bedtime)
Dose RangeUp to ~20 mg/day in divided doses
Common ADRsDizziness, headache, syncope, palpitations, GI discomfort


Prescription StatusPrescription-only

Summary

Prazopress‑ER 2.5 mg Tablet delivers long-acting blood pressure control and symptomatic relief for BPH and Raynaud's, with once-daily dosing and minimal rebound hypotension. The ER formulation improves tolerability and steady effect. Regular monitoring is advised, and use cautiously with other vasodilators or heart medications.

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