✅ Product Benefits
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Potent acid suppression — Inhibits gastric H⁺/K⁺‑ATPase (proton pumps) in parietal cells to significantly reduce stomach acid secretion
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Wide-ranging indications — Approved for duodenal and benign gastric ulcers, erosive GERD, maintenance therapy, Zollinger–Ellison syndrome, and H. pylori eradication when combined with antibiotics
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Convenient once-daily dosing — Standard adult dose is 20 mg once daily in the morning for 4–8 weeks; maintenance may be reduced to 10 mg once daily depending on response
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Rapid onset with sustained effect — Offers quick and durable control of gastric acid with a favorable drug profile and fewer CYP2C19-mediated interactions compared to some PPIs .
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Flexible administration — Can be taken with or without food, but swallowing whole without crushing ensures enteric coating efficacy
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Generally well tolerated — Common side effects include headache, nausea, diarrhea, abdominal pain, flatulence; serious risks like hypomagnesemia, B12 deficiency, kidney injury, osteoporosis-related fractures, skin reactions are rare .
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Low renal dosage adjustment requirements — No dose adjustment needed in renal impairment; pediatric dosing applies only in specific weight-based cases
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