💡 Uses & Benefits
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Dual-action blood sugar control: Sitagliptin boosts insulin and lowers glucagon via incretins; Metformin improves insulin sensitivity and reduces liver glucose output
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Convenient dosing: Taken twice daily with meals; starting at 50 mg/500 mg each dose helps reduce GI side effects
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Better glucose management: More effective than either drug alone, aiding in reducing HbA1c and risk of diabetes-related complications
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Widely accessible: Manufactured locally in Bangladesh; one strip (10 tablets) costs around ৳160
📋 Product Specifications
| Feature | Description |
|---|---|
| Active Ingredients | Sitagliptin 50 mg + Metformin HCl 500 mg |
| Formulation | Immediate-release film-coated tablet |
| Dosing | Twice daily with food; max 200 mg Sitagliptin / 2000 mg Metformin daily |
| Indication | Adjunct to diet and exercise for adults with type 2 diabetes |
| Manufacturer | Square Pharmaceuticals PLC, Bangladesh |
| Pack Size & Price | 10 tablets at ৳160 (approx ৳16 per tablet) |
📌 Highlights at a Glance
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✅ Comprehensive glucose control using two complementary mechanisms
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🥘 Meal-friendly dosing to reduce stomach upset
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💊 Affordable and widely available in Bangladesh
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🩺 Simplifies regimen by combining two oral medications in one tablet
⚠️ Important Safety & Precautions
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Common side effects: GI discomfort (diarrhea, nausea), headache, URTI
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Risk of hypoglycemia increases when used with insulin or sulfonylureas; monitor blood sugar closely
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Contraindications: Not for type 1 diabetes or diabetic ketoacidosis; caution in renal impairment and liver disease
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Rare but serious risk: Lactic acidosis—watch for symptoms like fast breathing, unusual fatigue, or stomach discomfort
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Drug interactions: Be cautious with alcohol, iodinated contrast, cimetidine, diuretics, steroids, and ACE inhibitors—monitor accordingly
💡 Patient Advice
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Take with meals to reduce GI upset.
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Monitor kidney function and vitamin B12 annually, as long-term Metformin use may impact both
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Avoid alcohol or use with caution; it may raise the risk of lactic acidosis
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Do not stop suddenly without your doctor’s advice—this may affect your blood sugar control.
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