✅ Product Benefits
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Dual-mode treatment:
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Tamsulosin (α₁A-blocker) relaxes prostate and bladder muscles for immediate symptom relief.
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Dutasteride (5α-reductase inhibitor) reduces DHT production to gradually shrink the prostate and treat underlying enlargement.
Together they offer faster and more lasting improvement than single drug therapy. turn0search3turn0search14turn0search6
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Effective symptom control: Quickly improves urinary flow, reduces urgency, frequency, hesitancy and incomplete bladder emptying. Dutasteride's benefits develop over weeks to months. turn0search4turn0search17turn0search2
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Convenient once-daily use: One capsule (~30 min after same meal daily) replaces separate pills, enhancing adherence. No dose adjustment needed for renal impairment. turn0search10turn0search2
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Accessible pricing: Priced at approximately ৳ 23 per capsule (~৳ 115 per strip of 5; ৳ 690 per box of 28), widely available in Bangladesh. turn0search0turn0search5turn0search16
ℹ️ Indications & Administration
Primary indication:
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Moderate-to-severe lower urinary tract symptoms due to benign prostatic hyperplasia; reduces risk of acute urinary retention and surgery.
Dosage:
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tamsulosin 0.4 mg + dutasteride 0.5 mg capsule, once daily, about 30 minutes after the same meal each day. turn0search0turn0search10
Onset of action:
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Tamsulosin: symptom relief in days to a few weeks.
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Dutasteride: prostate shrinkage typically apparent within 3–6 months. turn0search2turn0search6
⚠️ Safety, Side Effects & Precautions
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Common side effects:
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Dizziness, orthostatic hypotension
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Sexual dysfunction: reduced libido, impotence, retrograde ejaculation
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Breast tenderness or enlargement in men (gynecomastia)
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Headache, fatigue, rhinitis, nausea, diarrhea or constipation. turn0search14turn0search4turn0search7
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Key warnings:
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Pheochromocytoma contraindicated due to blood pressure risk.
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Monitor for orthostatic hypotension, especially at treatment start.
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Dutasteride lowers PSA levels—screening interpretation must account for this.
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Avoid blood donation for 6 months after discontinuation. turn0search2turn0search13turn0search4
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Drug interactions:
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Caution with CYP3A4 inhibitors (e.g., ketoconazole) increasing tamsulosin levels
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Avoid concurrent PDE‑5 inhibitors (e.g., sildenafil), other α-blockers, or CNS depressants due to additive hypotensive risk.
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Cimetidine may raise tamsulosin levels; furosemide may reduce them. turn0search4turn0search2turn0search17
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Contraindicated populations:
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Women (especially pregnant or of childbearing age); handling capsules may expose fetus to dutasteride.
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Men with severe hepatic impairment.
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Patients with allergy to tamsulosin or dutasteride. turn0search2turn0search0
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Overdose info:
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Tamsulosin overdose may cause severe hypotension; treat with fluids and supportive care.
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Dutasteride overdose risks rare due to wide safety margin, but supportive therapy recommended. turn0search5turn0search2
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📝 Summary Table
| Feature | Details |
|---|---|
| Components | Tamsulosin HCl 0.4 mg + Dutasteride 0.5 mg |
| Therapeutic Class | α₁A-blocker + 5α-reductase inhibitor combination |
| Indications | Moderate-to-severe BPH symptoms; prevention of retention/surgery |
| Dosage | One capsule daily (after same meal) |
| Tamsulosin Onset | Days to weeks |
| Dutasteride Effect Timeline | 3–6 months for prostate shrinkage |
| Common ADRs | Dizziness, sexual dysfunction, GI upset, breast effects |
| Precautions | Blood pressure effects, PSA suppression, avoid blood donation |
| Price in Bangladesh | ~৳ 23/capsule; strip ~৳ 115; 28-cap box ~৳ 690 |
| Manufacturer | UniMed UniHealth Pharmaceuticals Ltd., Bangladesh |
✅ In summary:
Uromax‑D offers faster symptom relief via tamsulosin and long-term prostate volume reduction with dutasteride in one convenient capsule—ideal when combination therapy is needed. Monitor for sexual side effects, hypotension, and PSA changes.
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