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✅ Product Benefits
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Dual pain-relief mechanism: Paracetamol provides fast antipyretic and analgesic action, while tramadol adds centrally acting opioid-like relief, targeting both nociceptive and neuropathic pain pathways. turn0search0turn0search1
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Rapid and sustained effects: Pain relief onset within an hour, lasting 4–6 hours. Suitable for acute or post-operative moderate to moderately severe pain. turn0search5turn0search9
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Effective short-term therapy: Recommended for no more than 5 days, minimizing risk of dependence and adverse effects. Flexible for use with or without food. turn0search0turn0search1
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Economical & accessible in BD: Costs around ৳ 8 per tablet (~৳ 90 per 10-tablet strip; ৳ 270 per 30-pack), making it affordable for general use. turn0search0turn0search2turn0search10
ℹ️ Usage & Dosing
| Age/Condition | Dose |
|---|---|
| Adults | 1–2 tablets every 4–6 hours (max 8 tablets/day) |
| Acute pain duration ≤5 days | Short-term regimen |
| Renal impairment (CrCl 10–30 mL/min) | Extend dosing interval to max 2 tablets every 12 h |
| Children (<18 years) | Not recommended |
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Take tablets whole (do not chew or crush), with or without food. turn0search0turn0search2
⚠️ Safety & Precautions
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Contraindications:
Hypersensitivity to tramadol, paracetamol, opioids; acute intoxications; uncontrolled epilepsy; severe hepatic impairment; concurrent use or recent withdrawal of MAO inhibitors. turn0search0turn0search2 -
Side effects:
May include asthenia, fatigue, dizziness, nausea, vomiting, headache, constipation or diarrhea, dry mouth, tremor, euphoria, confusion, insomnia, pruritus, increased sweating, dyspepsia. turn0search0turn0search1turn0search4 -
Warnings:
Avoid driving or operating machinery; avoid alcohol; not to be used with other tramadol or paracetamol products; caution if also using hypnotics, tranquilizers, or other opioids. Risk of dependence if misused. turn0search0turn0search4 -
Special populations:
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Renal impairment: lower dosage frequency advised.
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Hepatic disease: contraindicated.
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Geriatric: start cautiously due to increased risk of sedation and organ function decline.
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Pregnancy & lactation: Category C/thorough risk-benefit assessment; not recommended during breastfeeding. turn0search0turn0search1turn0search2
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📝 Quick Facts Table
| Feature | Details |
|---|---|
| Combination | Paracetamol 325 mg + Tramadol HCl 37.5 mg |
| Therapeutic use | Relief of moderate to moderately severe pain |
| Adult regimen | 1–2 tablets every 4–6 h, max 8/day, ≤5 days duration |
| Common reactions | Dizziness, nausea, constipation, drowsiness |
| Major precautions | Seizures (with MAOIs), dependence, respiratory depression |
| Approx. price (BD) | ৳ 8/tab; 10‑tab strip ~৳ 90; 30‑tab pack ~৳ 270 |
| Manufacturer | UniMed UniHealth Pharmaceuticals Ltd., Bangladesh |
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