✅ Benefits
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Reduces risk of CV death and HF hospitalization in adults with symptomatic chronic heart failure and reduced ejection fraction (<45%) following recent hospital admission or need for outpatient IV diuretics Dhakarx+10Medex+10Meds BD+10
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Works via soluble guanylate cyclase stimulation, enhancing cGMP production to relax blood vessels, improve cardiac contractility, and support reverse remodeling of the heart Meds BD+3Medex+3Best In Meds+3
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Flexible dosing protocol: start at 2.5 mg once daily with food; dose may be doubled every ~2 weeks up to a maintenance dose of 10 mg, as tolerated Pharmacist BD+4Medex+4ACME Laboratories Ltd.+4
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No dose adjustment needed in elderly patients, mild to moderate hepatic impairment, or chronic kidney disease (eGFR ≥ 15 mL/min)—data for dialysis patients is lacking Dhakarx+5Medex+5Meds BD+5
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Well absorbed with food (≈93% bioavailability)—must be taken with meals to optimize absorption ACME Laboratories Ltd.+2Medex+2Pharmacist BD+2
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Affordable price in Bangladesh—approx. ৳50 per tablet (~৳700 per 2×7 strip)
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