💊 Uses & Benefits
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Erectile Dysfunction (ED): Enhances ability to achieve and sustain an erection by selectively inhibiting PDE5 and increasing cGMP levels in penile tissues, only effective with sexual stimulation
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Pulmonary Arterial Hypertension (PAH): Helps lower pulmonary vascular resistance and improve exercise ability (off-label/secondary indication)
📋 Dosage & Administration
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Take 50 mg orally 30 minutes to 1 hour before sexual activity, maximum once daily. May adjust to 25 mg or up to 100 mg depending on response and tolerability
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For PAH, dose generally 20 mg three times daily, spaced 4–6 hours apart
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Elderly (>65 years) or patients with hepatic or renal impairment should start at 25 mg, with careful monitoring
⚠️ Side Effects & Precautions
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Common side effects: Headache (7–16%), flushing, dyspepsia, nasal congestion, dizziness, insomnia, diarrhea, skin rash, and visual disturbances (e.g., blue-green tint)
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Serious risks: Priapism, cardiovascular events including myocardial ischemia or arrhythmia, hearing loss, and vision loss—especially in patients with underlying heart conditions
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Drug interactions: Avoid with nitrate medications; CYP3A4 inhibitors (like ketoconazole, erythromycin, ritonavir) can increase sildenafil levels; inducers (e.g. rifampicin) can reduce its effect
🧪 Product Details & Availability (Bangladesh)
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Generic Name: Sildenafil Citrate
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Strength: 50 mg tablet
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Manufacturer: Square Pharmaceuticals Ltd.
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Price: Approx. ৳6–30 per tablet; Strip of 5 costs around ৳150 BDT depending on retailer
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Available nationwide in retail pharmacies and e-pharmacies like Pharmacypoint, MedEx, Arogga, etc.
📋 Quick Overview Table
| Feature | Description |
|---|---|
| Active Ingredient | Sildenafil Citrate |
| Strength | 50 mg Tablet |
| Primary Uses | Erectile Dysfunction, Pulmonary Arterial Hypertension |
| Typical Dose | 50 mg once daily (up to 100 mg); PAH: 20 mg TID |
| Key Benefits | Improves erectile performance, reduces pulmonary resistance |
| Common Side Effects | Headache, flushing, indigestion, visual changes |
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