✅ Product Benefits

1. Dual-action relief with gastric protection
   Naproxen provides potent anti-inflammatory and analgesic effects, while Esomeprazole reduces stomach acid to help prevent NSAID-associated gastric ulceration. 

2. Effective for arthritis management
   Indicated for relief of symptoms in osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, offering improved functional capacity and quality of life. 

3. Convenient dosing schedule
   Standard adult regimen: one tablet twice daily, taken at least 30 minutes before meals for optimal absorption and efficacy. Tablets should not be crushed, chewed, or dissolved. 

4. Minimized GI side effects
   The Esomeprazole component helps protect the gastric mucosa, reducing risks like dyspepsia, gastritis, and ulcers common with long-term NSAID use. 

5. Well-characterized safety profile
   Common side effects include gastritis, dyspepsia, abdominal pain, diarrhea, and nausea. Use caution in elderly, and in renal or hepatic impairment. Avoid in pregnancy and late pregnancy due to Naproxen’s fetal risks. 

6. Reduces cardiovascular and renal risk when used appropriately
   Using the lowest effective dose for the shortest duration is recommended, especially in patients with hypertension or heart disease, due to NSAID-related fluid retention and cardiovascular risk. 

7. Safe drug interaction profile
   Potential interaction with warfarin (increased bleeding risk), reduced absorption of ketoconazole, iron salts, digoxin due to altered gastric pH. Naproxen may lower effectiveness of ACE inhibitors, beta-blockers, and diuretics. 

8. Accessible and affordable option
   Priced at approximately ৳13 per tablet (strip of 10 ~৳130), widely available throughout Bangladesh in pharmacies and online. Comes in 375/20 mg and 500/20 mg strengths.